BACKGROUND: Obesity is a complex disorder and has been increasing globally at alarming rates including Pakistan.However, there is scarce research on understanding obesity genetics in Pakistan.Leptin is a hormone secreted by adipocytes in response to satiety and correlates with body weight.Any mutations in the LEP gene have an adverse effect on ener
Tea polyphenols attenuate staurosporine-induced cytotoxicity and apoptosis by modulating BDNF-TrkB/Akt and Erk1/2 signaling axis in hippocampal neurons
Tea polyphenols fp9550bk (TP) are the major ingredients in tea beverages that display health-benefits including anti-oxidation, anti-inflammation, anti-aging, attenuating blood pressure and deflating.In this study, we investigated the neuroprotective effects of TP to attenuate staurosporine (STS)-induced cytotoxicity.Rat hippocampal neurons were is
Territorial Prospective to Sustainability: Strategies for Future Successful of Water Resource Management on Andean Basins
In Latin America, water resource management in some areas is difficult when all parts of a system are not considered (including its dynamism).Therefore, it becomes necessary to prepare instruments that facilitate management using a comprehensive approach.This study aimed to develop a methodology that allows one to conduct a prospective analysis of
Nephrotic Syndrome: A Rare Sequelae of Varicella Zoster Infection
Nephrotic syndrome without haematuria following the sequelae of the infection is uncommon.The present case report describes nephrotic syndrome following varicella infection, without haematuria and hypertension in a 21-year-old young adult.The patient presented with four weeks history of fever, swelling of both feet and facial puffiness.General phys